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DSIP 5mg

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DSIP or Delta Sleep Inducing Peptide is a small peptide used by neurons in the brain to communicate. There are many of these type peptides and they all influence the brain in certain ways.

This particular peptide is found in several areas throughout the body and the exact mechanism by which it induces sleep is not exactly clear. It could be any one of a number of effects it exerts or a combination of many. It is present in the hpta, the brain, the melanocortin system, and various organs and tissues throughout the body.

It increases the release of Growth Hormone and decrease the release of Growth Hormone Inhibiting Hormone. It also decreases corticotropin (aka stress hormone). It is proven to improve SWS (slow wave sleep) and also impact the circadian rhythms working to reset your sleep clock if you will.

With all the things this does in the body, and all the places it is found, the bottom line is it is proven to help you sleep. It is proven effective in research as a treatment for narcolepsy and normalizing sleep patterns.

Refs:
*Obes Rev. 2009 Nov;10 Suppl 2:46-51.Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?Gimble JM, Ptitsyn AA, Goh BC, Hebert T, Yu G, Wu X, Zvonic S, Shi XM, Floyd ZE. SourceStem Cell Biology Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA. gimblejm@pbrc.edu
* Sudakova KV, Umriukhina PE, Rayevskyb KS (2004). "Delta-sleep inducing peptide and neuronal activity after glutamate microiontophoresis: the role of NMDA-receptors". Pathophysiology 11 (2): 81–86. doi:10.1016/j.pathophys.2004.03.003. PMID 15364118
* Iyer KS, Marks GA, Kastin AJ, and McCann SM (1988). "Evidence for a role of delta sleep-inducing peptide in slow-wave sleep and sleep-related growth hormone release in the rat". Proc Natl Acad Sci U S A 85 (10): 3653–3656. doi:10.1073/pnas.85.10.3653. PMC 280272. PMID 3368469

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